Purified Anti-Human CLEC-2 Antibody[AYP1] (AN008900P)
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| Alternate Names | member B, 1810061I13Rik, C type lectin domain family 1 member B, C type lectin like receptor 2, CLC1B_HUMAN, CLEC 2, CLEC 2B, CLEC-2, CLEC2B, C-type lectin domain family 1, C-type lectin domain family 1 member B, C-type lectin-like receptor 2, C-type lectin-like receptor-2, QDED721, UNQ, PRO, CLEC, CLEC2, CLEC1B, UNQ721, PRO1384 |
| Clone | |
| Verified Samples | Verified Samples in FCM: Human peripheral blood platelet cell |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume |
| Background | C-type lectin domain family 1 member B (CLEC1B, CLEC2) is a 32kD, type II transmembrane protein, highly expressed on platelets and megakaryocytes. CLEC1B is involved in platelet activation and aggregation, and mediates the capture of HIV-1 by platelets. CLEC1B contains one hem-immunoreceptor tyrosine-based activation motif (hemITAM) though which interact with Syk and PLC-g. The known ligands of CLEC1B are rhodocytin and podoplanin. |
| Immunogen | Recombinant Human CLEC-2 protein |
| Abbre | CLEC-2 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Isotype Control | Purified Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications |
FCM
|
| Research Areas | Immunology |
| Cellular Localization |
Membrane
|
| Tissue Specificity |
Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets.
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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